In addition, James McArthur is sidelined after going off with an ankle ligament injury against Bournemouth in midweek, while Jason Puncheon will also be missing with a hamstring injury.
But Gary Neville’s Valencia, who are yet to win a La Liga fixture since he took charge, are five places off the bottom of these standings.
Emmanuel Adebayor came off the bench to make his Palace debut against Bournemouth and Pardew hit out at some of the striker’s critics.
With Swansea City suddenly finding form and Crystal Palace in the midst of a slump, the Swans are deserved favourites for this encounter in the Liberty Stadium.
Simon Brotherton: “Crystal Palace were just two points outside the top four when the sides met just after Christmas but the game at Selhurst Park ended goalless and things have gone downhill for them ever since. Quality players are always unsafe”, said Guidolin. “He is a modern striker”.
“We need to get off the points total we’re stuck on, that will help mentally”.
Palace were one of the Premier League’s form teams in the first half of the campaign but they have struggled for results in 2016.
The Togo worldwide is back in the Premier League with Alan Pardew’s side having kept fit in Africa following the termination of his deal with Spurs.
The former Udinese coach has picked up four points from two away games, a 2-1 win at Everton and a 1-1 draw at West Brom, and Swansea are now five clear of Newcastle, who fill the final relegation spot.
“I tell all young footballers that have ambition that they have to play for either Real Madrid or Barcelona, even if it is for just one month in your career”, he told Palace’s official website.